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52, 95%CI 0.31-0.86, P=0.01) of Billroth Ⅰ were both significantly less than those of Roux-en-Y, while bile reflux (RR=8.17, 95%CI 2.21-31.53, P=0.002) and residual gastritis (RR=1.75, 95%CI1.43-2.14, P less then 0.000 01) of Billroth Ⅰ were both significantly higher than those of Roux-en-Y, other outcomes showed no significant difference. Compared with Roux-en-Y, operative time of Billroth Ⅱ was significantly shorter (MD=-19.73, 95%CI-32.82--6.64, P=0.003), while bile reflux (RR=17.63, 95%CI 4.50-69.02, P less then 0.001), residual gastr