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Using this research we desired locate a mathematical explanation for this negative correlation between dose and impact, to confirm its existence with extra clinical information, also to explore it further with Monte Carlo simulations. Immediately recorded dosing and result data from significantly more than 9,000 customers ended up being available for the evaluation. The anesthetics propofol and sevoflurane as well as the catecholamine norepinephrine had been titrated to defined im
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