https://www.selleckchem.com/pr....oducts/740-y-p-pdgfr
icits.BACKGROUND Hutchinson-Gilford Progeria syndrome (HGPS) is a rare lethal premature and accelerated aging disease caused by mutations in the lamin A/C gene. Nevertheless, the mechanisms of cellular damage, senescence, and accelerated aging in HGPS are not fully understood. Therefore, we aimed to screen potential key genes, pathways, and therapeutic agents of HGPS by using bioinformatics methods in this study. METHODS The gene expression profile of GSE113648 and GSE41751 were retrieved from the gene expression omnibus da
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