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919 (95% CI 0.865-0.973) for the training set and 0.900 (95% CI 0.812-0.988) for the validation set and its clinical utility was confirmed by the decision curve analysis. Conclusions The nomogram established showed the ability to predict NSLN metastases in patients with initial cN+ BC that downstaged to cN0 after NAC.Background and purpose Amino acid substitutions at the N-termini of glucagon-like peptide-1 (GLP-1) receptor agonist peptides result in distinct patterns of intracellular signalling, sub-cellular trafficking and efficacy in