https://www.selleckchem.com/pr....oducts/Nevirapine(Vi
Tumor- and T cell-intrinsic mechanisms of immune checkpoint inhibition (ICI) response were uncovered.Cancer cells with abnormal chromosome numbers were sensitive to spindle assembly checkpoint inhibition.Knockout of any of several noncanonical open reading frames (ORF) impaired cancer cell survival.The KRASG12C inhibitor sotorasib continues to impress in non-small cell lung cancer In the phase II CodeBreak 100 trial, the agent elicited responses in more than a third of patients and led to a median progression-free survival
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