https://www.selleckchem.com/pr....oducts/thiostrepton.
In general, patients with type 2 diabetes have lower cardiorespiratory fitness levels and perform exercise at lower intensities compared to healthy controls. Since metformin (MET) has been shown to increase the rate of perceived exertion (RPE) during exercise with a fixed intensity, MET may reduce self-selected exercise intensity. The aim of this study was to assess the effect of MET on self-selected exercise intensity. Healthy males were eligible for this crossover, counterbalanced study with two treatment periods MET and placebo