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Significantly lower PSw and Ew were observed in NAWM compared to WM (ΔPSw -11.9 mL/100 g/min, p less then .05; ΔEw -4.3%, p less then .01). Significantly lower Ew was observed in NAGM compared to GM (ΔEw -12.1%, p less then .01). Significantly lower PSw and CBF were observed in non-GBCA contrast enhancing lesions compared to NAWM (ΔPSw = -11.5 mL/100 g/min, p less then .05; ΔCBF = -8.1 mL/100 g/min, p less then .05). Ew was significantly higher in non-GBCA enhancing chronic MS lesions compared to NAWM (ΔEw = 1.6%, p less then .05). The l
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