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This article is protected by copyright. All rights reserved.The world is facing an explosive COVID-19 pandemic. Some cases rapidly develop deteriorating lung function, which causes deep hypoxaemia and requires urgent treatment. Many centres have started treating patients in the prone position and oxygenation has improved considerably in some cases. Questions have been raised regarding the mechanisms behind this. The mini-review provides some insights into the role of supine and prone body positions and summarises the latest understandi
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