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Results We found that age, percentage of female sex, N-terminal pro-B-type natriuretic peptide levels, Ang-2 levels (763.3 ± 264.9 vs. 579.7 ± 169.3 pg/mL, P less then 0.001), and the left atrial volume index were significantly higher in patients with impaired CFR than in patients with preserved CFR. Serum Ang-2 levels were negatively correlated with CFR (r = -0.386, P less then 0.001). Binary logistic regression analysis showed that Ang-2 (odds ratio 1.004, 95% confidence interval [CI] 1.001-1.006, P = 0.003) and age (odds ratio 1.088, 95

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