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Loss-of-function mutations in DNaseL13, the enzyme that restricts the amount of microparticle-associated DNA, cause SLE in humans and mice. In this issue of JEM, Hartl et al. (2021. J. Exp. Med.https//doi.org/10.1084/jem.20201138) uncover a reduction in plasma DNASE1L3 enzymatic activity due to the presence of autoantibodies in patients with nonfamilial SLE. To describe inmates' perceptions of healthcare quality in Catalonian prisons. Transversal study of 6,856 inmates in Catalan prisons in September 2017. Randomized simple screening w
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