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The inherent plasticity of clinically evolving cancer justifies approaches to characterize and prevent undesirable activation of early oncogenic pathways. CONCLUSIONS Study of the pattern of intracellular signal pathway activation by anticancer drugs can lead to development of efficient treatment strategies by reducing detrimental secondary effects. Copyright© Bentham Science Publishers; For any queries, please email at [email protected] Despite of many successes in discovery of numerous cancer chemotherapeutic agents f

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