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3×109/L, GRAN76%, LYM19%, neutrophil lymphocyte ratio3.87, Kalph-Kaliph leukocyte index of intoxication (LII) 3.4, Ostrovsky LII 2.8. Also we have found that GG genotype of IL10 gene polymorphism (rs1800872) leads to a 12.5-fold and CT genotype of RLN2 gene polymorphism (rs4742076) leads to a 17.0-fold increase in risk for PPROM. The prognostic model that we have suggested is an adequate and convenient instrument for practical medical use, which allows for assessment of PPROM probability with a 85% sensitivity and a
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