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50 seconds of disintegration time, the index expanding at the 15 second by 242.29% and the cumulative percent of the drug at 80 seconds by 98.08%. CONCLUSION Amlodipine besylate can be formulated into fast orally dissolving film preparations using HPMC and crospovidone polymers so that they may be considered for use in the treatment of hypertension for patients with drug-induced problems in tablet or capsule form. Copyright © 2019 Sumaiyah Sumaiyah, Julia Mentari, Suryanto Suryanto.AIM The research aimed to determine the cytotoxic activ

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