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prospectively applied to an outpatient population with COVID-19 identified populations with low, intermediate, and high risk of hospitalization. Significant uncertainty has existed about the safety of reopening college and university campuses before the COVID-19 pandemic is better controlled. Moreover, little is known about the effects that on-campus students may have on local higher-risk communities. We aimed to estimate the range of potential community and campus COVID-19 exposures, infections, and mortality under various university