https://www.selleckchem.com/pr....oducts/17-DMAG,Hydro
Chronic, low-grade systemic, and mucosal inflammation correlates with increased morbidity and poor clinical outcomes among patients with HIV. These long-term complications are linked to the disruption of gastrointestinal (GI) tract epithelial barrier integrity and subsequent microbial translocation. However, the mechanisms responsible for these downstream effects of infection are unknown. Here we demonstrate that during the disruption of the GI tract and increased microbial translocation, we find inflammatory cytokine