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2; LCFAs long-chain fatty acids; LFQ-MS label-free quantitation mass spectrometry; LPC lysophoshatidylcholine; MAP1LC3B/LC3B microtubule associated protein 1 light chain 3 beta; MTOR mechanistic target of rapamycin kinase; PBD peroxisome biogenesis disorders; PTS1 peroxisomal targeting signal 1; ROS reactive oxygen species; sgRNA single guide RNA; VLCFAs very-long chain fatty acids; Vor vorinostat; WO wash-off. To study the prevalence of abnormalities of the septi pellucidi (SP) in a cohort of fetuses with open spinal dysraphism (OSD)

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