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s. 10 were significantly associated with adverse clinical outcomes. Larger epidemiologic studies are required to confirm these associations.Background Minimally invasive surgical (MIS) techniques for pilonidal sinus disease (PNS) have gained popularity in recent years, due to faster recovery and lower complication rate compared with conventional methods. Our aim was to assess recurrence rate following MIS Trephine procedure for PNS and to identify possible risk factors for recurrence. Materials and Methods A prospective cohort, inclu