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Metabolic moving between glycolysis and mitochondrial oxidative phosphorylation has-been implicated in macrophage polarization. M1 macrophages primarily rely on glycolysis, whereas M2 macrophages count on the tricarboxylic acid period and oxidative phosphorylation; hence, elements that affect macrophage metabolic rate may disrupt M1/M2 homeostasis and exacerbate irritation. The components through which obesity and hypertension may synergistically induce macrophage metabolic

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