https://www.selleckchem.com/pr....oducts/bgj398-nvp-bg
PDQ decreased the expression and mRNA levels of HIF-1α and its downstream factor GLUT1. Moreover, the dSTORM results showed that PDQ reduced GLUT1 expression on the cell membrane and inhibited GLUT1 clustering. Our work showed that the antitumour effect of PDQ was related to the downregulation of the HIF-1α-GLUT1 pathway, suggesting that PDQ could be a potential therapeutic agent for hypopharyngeal cancer treatment. Our work showed that the antitumour effect of PDQ was related to the downregulation of the HIF-1α-GLUT1 pathway,
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