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Statistically significant differences were not found in any of the salivary markers examined between the children with nephrotic syndrome who were treatment sensitive ( = 19) and resistant ( = 8). Protein and IL-8 salivary levels were lower in the active ( = 7) than in the remission ( = 2 group. Salivary parameters distinguished children with nephrotic syndrome in relapse from healthy children. This may be due to decreased salivary protein excretion, which reflects decreased plasma levels, consequent to proteinuria. Accordingly, saliv
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