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Histopathology revealed severe multifocal dermatitis with abundant Leishmania amastigotes within the cytoplasm of phagocytic cells, depletion of lymphocytes in lymphoid tissues, interstitial pneumonia, and interstitial nephritis. Tissue samples were positive for Leishmania by PCR. Conclusion The macro- and microscopic changes correlated with the presence of Leishmania as established by serological test and PCR. © 2020 Y. Picón et al. published by Sciendo.Introduction The aim of the study was to establish the prevalence of Bartonella spp. in cats in eastern