https://www.selleckchem.com/pr....oducts/pf-3644022.ht
Global metabolomic profiling showed that conventional mice had greater variability in their metabolic response to injury, and a more distinct joint metabolome compared to their corresponding controls. Furthermore, differences in the response to injury in GF compared to conventional mice were linked to mouse metabolic pathways that regulate inflammation associated with the innate immune system. These results suggest that the gut microbiota promote the development of PTOA during the acute phase following joint trauma possibly through t
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