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This paper investigates the associations of income segregation with homicide mortality across 152 cities in Brazil. Despite GDP increases, an important proportion of the Brazilian population experiences poverty and extreme poverty. Segregation refers to the way that different groups are located in space based on their socioeconomic status, with groups defined based on education, unemployment, race, age, or income levels. As a measure of segregation, the dissimilarity index showed that overall, it would be necessary to relocate 29.7% of