https://www.selleckchem.com/pr....oducts/sar439859.htm
BACKGROUND T regulatory type 1 (Tr1) cells are a class of regulatory T cells participating in peripheral tolerance, hence the rationale behind their testing in clinical trials in different disease settings. One of their applications is tolerance induction to allogeneic islets for long-term diabetes-free survival. Currently the cellular and molecular mechanisms that promote Tr1-cell induction in vivo remain poorly understood. METHODS We employed a mouse model of transplant tolerance where treatment with G-CSF/Rapamycin induces permanen
Like
Comment
Share
