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e to perform concomitant microbiome analyses. Video abstract. The relationship between antibiotic use and antimicrobial resistance varies with cultural, socio-economic, and environmental factors. We examined these relationships in Kibera, an informal settlement in Nairobi-Kenya, characterized by high population density, high burden of respiratory disease and diarrhea. Two-hundred households were enrolled in a 5-month longitudinal study. One adult (≥ 18years) and one child (≤ 5years) participated per household. Biweekly interviews (n = 1

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