https://www.selleckchem.com/pr....oducts/5-n-ethylcarb
" These sites are buried on the inhibitor-unbound surface but become apparent when the inhibitor is bound. In addition, an alternative method based on cell-free protein synthesis of protein kinases may allow the discovery of small molecules that occupy these mysterious binding sites. Transitional folding intermediates would become alternative targets in drug discovery, enabling the efficient development of potent kinase inhibitors.The amyloid-β (Aβ) peptides are associated with two prominent diseases in the brain,