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022) and gamma-glutamyltransferase (p = 0.015). The homozygous minor allele genotype (TT) was associated with a decrease in glucose levels. CONCLUSION The homozygous minor allele genotype of the rs11187533 SNP might be protective against metabolic consequences accompanying obesity and could allow the identification of metabolically healthy obese individuals at early ages. © 2020 S. Karger AG, Basel.Determining the optimal vaccination strategy for the protection of the elderly population against pneumococcal disease remains a challenge.