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Hence, it is necessary to review the pathogenic systems of V. mediterranei to bivalve larvae. We discovered that V. mediterranei was the pathogen of larval bivalve vibriosis, as well as its extracellular items contributed a vital role for virulence in juveniles. This research is initial report of V. mediterranei as a causative agent for vibriosis in bivalve juveniles. Our results offer valuable information for knowing the pathogenic system of V. mediterranei to b
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