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e., ( value 0.05) but in both groups I and II, there was a statistical significant difference when comparing with group III i.e., ( 0.05). Thus, and propolis-modified GIC provided higher antibacterial effect with increased level of inhibition against the and ; hence, it can be used as a choice of restorative material to treat dental caries. Further studies are required to determine the physical and mechanical characteristics of the material. Paulraj J, Nagar P. Antimicrobial Efficacy of and Propolis-modified Glass Ionomer Cem