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5%) compared with 2006-07 (10.6%). Our results indicate an increase in high-risk HPV types in women and a rather stable exposure in men. No clear effects of the strategy of girls-only vaccination were observed in men, probably because of the short time after introduction combined with suboptimal coverage. No herd immunity has been observed yet in a population with suboptimal HPV vaccination coverage. No herd immunity has been observed yet in a population with suboptimal HPV vaccination coverage. Insulin-like growth factor-1 (IGF-1) has