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ADHD Medication UK For Adults The first prescription medication is typically an stimulant, such as methylphenidate. It boosts the activity of areas of the brain which regulate behavior and attention. Long-acting formulations are also on the market and are the preferred treatment for adults suffering from ADHD. They are slowly absorbed into the bloodstream and avoid the 'crash' that could be experienced when short-acting drugs wear off. Stimulants Stimulants, which boost levels of dopamine and norepinephrine in the brain are the most commonly used treatment for AD