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This has been highlighted that ambient concentrations may bring about side effects on wild bivalves after long-term exposures. Also, higher trophic degree organisms may be much more impacted as a result of food-chain transfer (age.g., humans tend to be shellfish consumers). Overall, the three chosen NSAIDs were reported to bioconcentrate in marine bivalves, with acknowledged impacts at various life-stages. Immune responses were the key target of a long-term exposure to the medicatio
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