https://www.selleckchem.com/pr....oducts/incb28060.htm
Furthermore, the increase in the mRNA expression of α-SMA was well correlated with cyclin-dependent kinase inhibitor 1A, a cell cycle arrest marker, but not with BCL-2 binding component 3 and Fas cell surface death receptor, which are both pro-apoptotic factors, indicating that the MTX-induced EMT may be related to cell cycle arrest, but not to apoptosis. These findings suggested that different mechanisms were involved in the MTX-induced EMT and apoptosis.Microsomal epoxide hydrolase/epoxide hydrolase 1 (mEH/EPHX1) works in conjunctio
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