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To assess the agreement between cardiac output estimated by two-dimensional echocardiography and bioreactance methods at rest and during dobutamine stress test in heart failure patients with preserved left ventricular ejection fraction (HFpEF). Hemodynamic measurements were assessed in 20 stable HFpEF patients (12 females; aged 61±7years) using echocardiography and bioreactance methods during rest and dobutamine stress test at increment dosages of 5, 10, 15, and 20μg/kg/min until maximal dose was achieved or symptoms and sign occurred,