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00 (95% CI 0.53, 1.88). The HR was 1.12 (95% CI 0.71, 1.76) for all bleedings. Hazard ratios for GI bleeding were 0.61 (95% CI 0.25, 1.52) for patients with upper GI cancer, and 0.92 (95% CI 0.58, 1.46) in patients with colorectal cancer. Evidence from this nationwide cohort study suggests a comparable 1-year risk of bleeding associated with DOAC compared with VKA among patients with AF and GI cancer. Evidence from this nationwide cohort study suggests a comparable 1-year risk of bleeding associated with DOAC compared with VKA among pati