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The bacterial burden increased exponentially, and an isoniazid dosage corresponding to 15 mg·L internal concentration (minimum inhibitory concentration) contributes to bacteriostasis for the mycobacterial illness when you look at the zebrafish. The concentration-effect commitment ended up being quantified, and considering that commitment and the translational elements, the isoniazid response ended up being translated to humans, which correlated well with observed information. This pr