https://www.selleckchem.com/pr....oducts/jnj-42226314.
0001) and increase the levels of IgA and IgM (P less then 0.0001) in the plasma of weaned piglets. In addition, dietary PQQ increased (P less then 0.05) the mRNA levels of antioxidant genes (NQO1, UGT1A1, and EPHX1), thereby enhancing (oxidized) nicotinamide adenine dinucleotide (NAD+) concentration and sirtuin 1 (SIRT1) activity in tissues. However, the addition of 200 mg kg-1 VC to the diet containing PQQ reduced most of the effects of PQQ. We further show that PQQ reduced (P less then 0.05) the expression of inflammation-related