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The most typical bad event had been stress, occurring in five (42%) patients. Pharmacokinetic analysis showed no appropriate medicine interactions between CDI-31244, sofosbuvir, and velpatasvir. In this pilot study of short-duration combo treatment involving a novel NNI with a fixed-combination DAA, 8 of 12 treatment-naïve patients with persistent genotype 1 HCV infection without cirrhosis achieved virologic remedy. Future trials might examine whether extending the NNI extent beyon