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Among all patients, RFS and OS were significantly longer in patients with MPV≤8.5 fL and PDW16 fL (p16% had significantly longer RFS than that in individuals with PDW ≤16 fL among stage III clients (p less then 0.001). In multivariate analysis, stage, perineural invasion, lymphovascular invasion, adjuvant therapy, CEA, CA19-9, PDW, and MPV had been found the most significant elements influencing RFS. SUMMARY Our research shows that elevated MPV and decreased PDW appear to be