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Interestingly, mechanistic studies and Nanostring data claim that AS602801 likely activates JNK signaling to induce apoptosis. Since AS602801 had adequate security and poisoning profile to advance from period we to stage II in clinical studies, repurposing of the ingredient may portray an opportunity for rapid interpretation for clinical therapy of CRPC patients. HYPOTHESIS Mechanistic understanding of particle-flocculant communications as well as its link to the ensuing floc framework is