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33%), dyslipidemia (44% vs. 50%), and diabetes (29% vs. 41%), as well as being less likely to have a history of smoking (10% vs. 15%) compared with males. Mortality differences were mostly attributable to the female subgroup who were revascularized above the knee (hazard ratio, HR 0.78, 95% CI 0.64-0.95), while no statistically significant differences were observed in males. This study found that females treated above the knee benefited from paclitaxel-coated devices, while no differences were found in males. Ongoing and future registri