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Two-dimensional and multidimensional here refer to the use of at the very least two separation stages for analysis, but extensive 2DGC today is apparently set aside for the GC×GC method. This could be classified from comprehensive MDGC (CMDGC) by just the evaluation time assigned into the second (2D) column, even though there does not seem to be a certain meaning that relates to this analysis time parameter. A number of different execution protocols for e