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Leads to normal chow rats, constant light exposure led to glucose abnormalities and dyslipidemia. In high-fat-fed rats, continual light exposure exacerbated sugar abnormalities, dyslipidemia, insulin opposition, and irritation and aggravated steatohepatitis. In contrast to HFD-LD rats, HFD-LL had reduced plasma sphingosine-1-phosphate and elevated liver concentrations of complete ceramide and specific ceramide types (ceramide d180/240, ceramide d181/220, ceramide d181/240
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