https://www.selleckchem.com/pr....oducts/740-y-p-pdgfr
e I alveolar epithelial cells, while the corresponding expression decreased after the addition of TLR2/4 inhibitors. Ozone exposure causes lung injury in a dose- and gender-dependent manner, and is more severe in males. When injured, the levels of HMGB1 and HA in BALF increased, which interact with TLR 2/4 to activate the downstream NF-κB signaling pathway. Further activating the NLRP3 inflammasome complex and regulating the ozone-induced pyroptosis. Ozone exposure causes lung injury in a dose- and gender-dependent manner,
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