https://www.selleckchem.com/pr....oducts/nf-kb-activat
Gsk343 (methyltransferase EZH2 inhibitor) (1mM) and U0126 (inhibitor of MEK1/2) (10μM) were used to show the specific effect of PBDEs. PBDE inhalation might promote inflammation/cancer via EZH2 methyltransferase activity and H3K27me3, k-RAS and ERk1/2 involvement, generating adverse health outcomes of the human lung. PBDE inhalation might promote inflammation/cancer via EZH2 methyltransferase activity and H3K27me3, k-RAS and ERk1/2 involvement, generating adverse health outcomes of the human lung. The present study aims to det