https://www.selleckchem.com/pr....oducts/pkc-theta-inh
ever, all hemoglobins derive from a clade I globin, or cytoglobin, probably involved in intracellular O transit and regulation. The annelid Platynereis is remarkable in having a large family of extracellular blood globins, while retaining all clades of ancestral bilaterian globins. We uncover a complex "pre-blood" evolution of globins, with an early gene radiation in ancestral bilaterians. Circulating hemoglobins in various bilaterian groups evolved convergently, presumably in correlation with animal size and activity. Howev