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05) at week 12. The serum BGP and BMP-2 concentration in the PEMF and ALN groups was increased (P less then 0.05) at week 2, but this increase was not synchronized. After 8 weeks, BGP and BMP-2 level in the PEMF group was observably elevated (P less then 0.01) in contrast to the ALN group. CONCLUSION From the experimental time interval analysis, PEMF can improve the mechanical stability of bone structure more gently and permanently than alendronate.BACKGROUND In hospitals, some problems still exist, such as transfusion reaction that can