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Merkelcell carcinoma (MCC) management typically includes surgery with or without adjuvant radiation therapy (aRT). Major challenges include determining surgical margin size and whether aRT is indicated. To assess the association of aRT, surgical margin size, and MCC local recurrence. Analysis of 188 MCC cases presenting without clinical nodal involvement. aRT-treated patients tended to have higher-risk tumors (larger diameter, positive microscopic margins, immunosuppression) yet had fewer local recurrences (LRs) than patients treated wit
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