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Introduction Biologic treatments are a milestone in the management of rheumatoid arthritis (RA) patients with an inadequate response to conventional synthetic treatments. With the increase in the number of biologic treatments, predictor factors of discontinuation are needed to choose the right treatment for the right patient.Areas covered In this article, the factors affecting persistence with biologic treatments will be covered factors associated with the demographic characteristics and comordidities of the patients, those with the ch
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