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76 ± 8 years, p = 0.008). Patients with moderately decreased estimated glomerular filtration rate (eGFR) had a higher frequency of HTPR than patients with slightly decreased eGFR or normal eGFR (35.8, 22.5, 12.2%, respectively, p 0.05). In multivariate analysis, an independent risk factor for HTPR was the eGFR (OR 0.984, 95% CI 0.980-0.988, p 0.001). Advanced age and decreased eGFR are correlated with poor pharmacodynamic response to aspirin. Advanced age and decreased eGFR are correlated with poor pharmacodynamic response to a